
Expression of the intracellular type amastigote particular genes within the Leishmania donovani parasite performs a serious position in parasite replication within the macrophage. Within the present work, we’ve characterised a novel hypothetical gene, Ld30b that’s particularly transcribed within the intracellular stage of the parasite. The recombinant Ld30b protein exists as a pentamer in answer as recognized by native-PAGE and measurement exclusion gel chromatography.
Structural evaluation utilizing round dichroism and molecular modeling point out that Ld30b belongs to household of cAMP-dependent protein kinase sort I-alpha regulatory subunit. Co-localization immunofluorescence microscopy and western blot analyses (utilizing anti-Ld30b antibody and anti-hypoxanthine-guanine phosphoribosyl transferase, a glycosome marker) on the remoted parasite glycosome organelle fractions present that Ld30b is localized in glycosome, although lacked a glycosome focusing on PTS1/2 sign within the protein sequence.
Episomal expression of Ld30b within the parasite precipitated the arrest of promastigotes and amastigotes progress in vitro. Cell cycle evaluation utilizing movement cytometry signifies that these parasites are arrested in ‘sub G0/G1’ section of the cell cycle. Single allele knockout of Ld30b within the parasite equally attenuated its progress by accumulation of cells within the S section of cell cycle, thus confirming the possible significance of acceptable stage of protein within the cells. Finding out such intracellular stage expressing genes may unravel novel regulatory pathways for the event of medicine or vaccine candidates towards leishmaniasis.
A big-scale expression technique for multimeric extracellular protein complexes utilizing Drosophila S2 cells and its software to the recombinant expression of heterodimeric ligand-binding domains of style receptor.
Most of the extracellular proteins or extracellular domains of plasma membrane proteins exist or operate as homo- or heteromeric multimer protein complexes. Profitable recombinant manufacturing of such proteins is usually achieved by co-expression of the parts utilizing eukaryotic cells by way of the secretory pathway. Right here we report a method addressing large-scale expression of hetero-multimeric extracellular domains of plasma membrane proteins and its software to the extracellular domains of a style receptor.
The goal receptor consists of a heterodimer of T1r2 and T1r3 proteins, and their extracellular ligand binding domains (LBDs) are accountable for the notion of main style substances. Nonetheless, regardless of the useful significance, recombinant manufacturing of the heterodimeric proteins has to this point been unsuccessful. We achieved the profitable preparation of the heterodimeric LBD by use of Drosophila S2 cells, which have a excessive secretory capability, and by the institution of a secure high-expression clone producing each subunits at a comparable stage.
The strategy overcame the issues encountered within the typical transient expression of the receptor protein in insect cells utilizing baculovirus or vector lipofection, which failed within the correct heterodimer manufacturing due to the biased expression of T1r3LBD over T1r2LBD. The big-scale expression methodology reported right here might function one of many appreciable methods for the preparation of multimeric extracellular protein complexes.
Fourier Remodel-Ion Cyclotron Resonance Mass Spectrometry as a Platform for Characterizing Multimeric Membrane Protein Complexes.
Membrane protein characterization is constantly hampered by challenges with expression, purification, and solubilization. Amongst a number of biophysical strategies employed for his or her characterization, native-mass spectrometry (MS) has emerged as a strong software for the evaluation of membrane proteins and complexes. Right here, two MS platforms, the FT-ICR and Q-ToF, have been explored to research the homotetrameric water channel protein, AquaporinZ (AqpZ), beneath non-denaturing circumstances.
This 97 kDa membrane protein advanced will be readily liberated from the octylglucoside (OG) detergent micelle beneath a variety of instrument circumstances on each MS platforms. Growing the utilized collision power of the FT-ICR collision cell yielded various levels of tetramer (97 kDa) liberation from the OG micelles, in addition to dissociation into the trimeric (72 kDa) and monomeric (24 kDa) substituents.
Tandem-MS on the Q-ToF yielded increased depth tetramer sign and, relying on the m/z area chosen, the noticed monomer sign assorted in depth. Precursor ion collection of an m/z vary above the anticipated protein sign distribution, adopted by gentle collisional activation, is ready to effectively liberate AqpZ with a excessive S/N ratio. The tetrameric cost state distribution obtained on each devices demonstrated superpositioning of a number of proteoforms because of various levels of N-terminal formylation. Graphical Summary ᅟ
The most important outer sheath protein kinds distinct conformers and multimeric complexes within the outer membrane and periplasm of Treponema denticola.
The most important outer sheath protein (MOSP) is a outstanding constituent of the cell envelope of Treponema denticola (TDE) and one in every of its principal virulence determinants. Bioinformatics predicts that MOSP consists of N- and C-terminal domains, MOSPN and MOSPC. Biophysical evaluation of constructs refolded in vitro demonstrated that MOSPC, beforehand proven to own porin exercise, kinds amphiphilic trimers, whereas MOSPN kinds an prolonged hydrophilic monomer.
In TDE and E. coli expressing MOSP with a PelB sign sequence (PelB-MOSP), MOSPC is OM-embedded and surface-exposed, whereas MOSPN resides within the periplasm. Immunofluorescence assay, floor proteolysis, and novel cell fractionation schemes revealed that MOSP in TDE exists as outer membrane (OM) and periplasmic trimeric conformers; PelB-MOSP, in distinction, fashioned solely OM-MOSP trimers.
Though each conformers type hetero-oligomeric complexes in TDE, solely OM-MOSP associates with dentilisin. Mass spectrometry (MS) indicated that OM-MOSP interacts with proteins along with dentilisin, most notably, oligopeptide-binding proteins (OBPs) and the β-barrel of BamA. MS additionally recognized candidate companions for periplasmic MOSP, together with TDE1658, a spirochete-specific SurA/PrsA ortholog.
anti-NQO1 |
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YF-PA11356 | Abfrontier | 100 ug | EUR 483.6 |
Description: Rabbit polyclonal to NQO1 |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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DLR-NQO1-Mu-48T | DL Develop | 48T | EUR 679.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse NADH Dehydrogenase, Quinone 1 (NQO1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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DLR-NQO1-Mu-96T | DL Develop | 96T | EUR 889.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse NADH Dehydrogenase, Quinone 1 (NQO1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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DLR-NQO1-Ra-48T | DL Develop | 48T | EUR 708 |
Description: A sandwich quantitative ELISA assay kit for detection of Rat NADH Dehydrogenase, Quinone 1 (NQO1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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DLR-NQO1-Ra-96T | DL Develop | 96T | EUR 928.8 |
Description: A sandwich quantitative ELISA assay kit for detection of Rat NADH Dehydrogenase, Quinone 1 (NQO1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RD-NQO1-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 692.4 |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RD-NQO1-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 962.4 |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RD-NQO1-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 723.6 |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RD-NQO1-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 1008 |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RDR-NQO1-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 723.6 |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RDR-NQO1-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 1008 |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RDR-NQO1-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 757.2 |
Rat NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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RDR-NQO1-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 1056 |
anti- NQO1 antibody |
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FNab05830 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against NQO1 |
anti-NQO1 (4D12) |
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LF-MA30655 | Abfrontier | 100 ul | EUR 632.4 |
Description: Mouse Monoclonal to NQO1 |
anti-NQO1 (1A11) |
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LF-MA30656 | Abfrontier | 100 ul | EUR 632.4 |
Description: Mouse Monoclonal to NQO1 |
Anti-NQO1 antibody |
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PAab05830 | Lifescience Market | 100 ug | EUR 426 |
Anti-NQO1 Antibody |
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PB9497 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-NQO1 antibody |
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STJ24804 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Anti-NQO1 antibody |
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STJ24805 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Anti-NQO1 antibody |
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STJ70143 | St John's Laboratory | 100 µg | EUR 430.8 |
Anti-NQO1 antibody |
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STJ94551 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to NQO1. |
Rabbit Polyclonal antibody Anti-CRBN |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
NQO1 Recombinant Protein (Human) |
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RP078738 | ABM | 100 ug | Ask for price |
Anti-NQO1 (1E3-A6) |
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YF-MA12677 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to NQO1 |
NQO1, human recombinant |
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7571-10 | Biovision | EUR 392.4 |
NQO1, human recombinant |
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7571-50 | Biovision | EUR 1123.2 |
Human NQO1 Antibody |
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32959-05111 | AssayPro | 150 ug | EUR 313.2 |
Nqo1/ Rat Nqo1 ELISA Kit |
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ELI-06921r | Lifescience Market | 96 Tests | EUR 1063.2 |
Polyclonal Goat Anti-NQO1 Antibody |
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AMM05061G | Leading Biology | 0.1 mg | EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-NQO1 . This antibody is tested and proven to work in the following applications: |
Anti-NQO1 Monoclonal Antibody (A180) |
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M00494-1 | BosterBio | 200ug | EUR 597.6 |
Description: Mouse Monoclonal NQO1 Antibody (A180). Validated in WB and tested in Human. |
Anti-NQO1 (isoform a) antibody |
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STJ72517 | St John's Laboratory | 100 µg | EUR 430.8 |
NQO1 Antibody |
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1-CSB-PA102829 | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
NQO1 Antibody |
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1-CSB-PA003475 | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
NQO1 Antibody |
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DF6437 | Affbiotech | 200ul | EUR 420 |
NQO1 siRNA |
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20-abx926309 | Abbexa |
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NQO1 siRNA |
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20-abx926310 | Abbexa |
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NQO1 Antibody |
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1-CSB-PA016039GA01HU | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF |
NQO1 Antibody |
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1-CSB-PA016039LA01HU | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
NQO1 Antibody |
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1-CSB-PA890070 | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
NQO1 antibody |
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70R-49661 | Fitzgerald | 100 ul | EUR 292.8 |
Description: Purified Polyclonal NQO1 antibody |
NQO1 Antibody |
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32295-100ul | SAB | 100ul | EUR 302.4 |
NQO1 Peptide |
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45-981P | ProSci | 0.1 mg | EUR 405.6 |
Description: NQO1 Peptide |
NQO1 Antibody |
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49364-100ul | SAB | 100ul | EUR 399.6 |
NQO1 Antibody |
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49364-50ul | SAB | 50ul | EUR 286.8 |
NQO1 antibody |
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70R-10256 | Fitzgerald | 50 ug | EUR 560.4 |
Description: Affinity purified rabbit polyclonal NQO1 antibody |
NQO1 antibody |
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70R-10257 | Fitzgerald | 50 ug | EUR 560.4 |
Description: Affinity purified rabbit polyclonal NQO1 antibody |
NQO1 antibody |
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70R-12504 | Fitzgerald | 100 ul | EUR 548.4 |
Description: Affinity purified Rabbit polyclonal NQO1 antibody |
NQO1 antibody |
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70R-18946 | Fitzgerald | 50 ul | EUR 522 |
Description: Rabbit polyclonal NQO1 antibody |
NQO1 Peptide |
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42-451P | ProSci | 0.1 mg | EUR 405.6 |
Description: (IN) NQO1 Peptide |
NQO1 antibody |
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22937-100ul | SAB | 100ul | EUR 468 |
NQO1 Antibody |
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35365-100ul | SAB | 100ul | EUR 468 |
NQO1 Antibody |
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3639-100 | Biovision | EUR 418.8 |
NQO1 Antibody |
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3639-30T | Biovision | EUR 175.2 |
NQO1 Antibody |
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31283-100ul | SAB | 100ul | EUR 302.4 |
NQO1 Antibody |
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31283-50ul | SAB | 50ul | EUR 224.4 |
NQO1 Antibody |
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ABD6437 | Lifescience Market | 100 ug | EUR 525.6 |
NQO1 siRNA |
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20-abx903636 | Abbexa |
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h NQO1 |
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LVP1058 | GenTarget | 1x107 IFU/ml x 200ul | EUR 541.2 |
Description: Pre-made over-expression lentivirus for expressing human target: NQO1 (NAD(P)H quinone dehydrogenase 1), [alternative names: DHQU; DIA4; DTD; NMOR1; NMORI; QR1]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_000903. It also contains a RFP-Blasticidin dual selection marker. |
pOTB7-NQO1 |
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PVT14601 | Lifescience Market | 2 ug | EUR 594 |
NQO1 Antibody |
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F50335-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
NQO1 Antibody |
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F50335-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
NQO1 Antibody |
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N1103-100UG | NSJ Bioreagents | 100 ug | EUR 419 |
NQO1 Antibody |
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N1103-25UG | NSJ Bioreagents | 25 ug | EUR 209 |
NQO1 Antibody |
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R31977 | NSJ Bioreagents | 100 ug | EUR 419 |
NQO1 Antibody |
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R33500-100UG | NSJ Bioreagents | 100 ug | EUR 399 |
NQO1 Antibody |
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R35927-100UG | NSJ Bioreagents | 100 ug | EUR 399 |
NQO1 Antibody |
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RQ5489 | NSJ Bioreagents | 100 ul | EUR 419 |
NQO1 protein (His tag) |
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80R-1197 | Fitzgerald | 100 ug | EUR 703.2 |
Description: Purified recombinant Human NQO1 protein |
NQO1 Recombinant Protein (Rat) |
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RP214418 | ABM | 100 ug | Ask for price |
NQO1 Recombinant Protein (Mouse) |
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RP154820 | ABM | 100 ug | Ask for price |
Human NQO1 shRNA Plasmid |
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20-abx951197 | Abbexa |
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Human NQO1 ELISA Kit |
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ELA-E2154h | Lifescience Market | 96 Tests | EUR 988.8 |
NQO1 ELISA KIT|Human |
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EF006205 | Lifescience Market | 96 Tests | EUR 826.8 |
Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST μ-form |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST p-form |
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GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
NQO1 Blocking Peptide |
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DF6437-BP | Affbiotech | 1mg | EUR 234 |
NQO1 Conjugated Antibody |
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C31283 | SAB | 100ul | EUR 476.4 |
NQO1 Conjugated Antibody |
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C32295 | SAB | 100ul | EUR 476.4 |
NQO1 Conjugated Antibody |
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C49364 | SAB | 100ul | EUR 476.4 |
NQO1 Polyclonal Antibody |
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ES2983-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against NQO1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
NQO1 Polyclonal Antibody |
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ES2983-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against NQO1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
NQO1 ELISA Kit |
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55R-1433 | Fitzgerald | 100 assays | EUR 1743.6 |
Description: ELISA kit for detection of NQO1 in the research laboratory |
NQO1 Rabbit pAb |
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A1518-100ul | Abclonal | 100 ul | EUR 369.6 |
NQO1 Rabbit pAb |
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A1518-200ul | Abclonal | 200 ul | EUR 550.8 |
NQO1 Rabbit pAb |
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A1518-20ul | Abclonal | 20 ul | EUR 219.6 |
NQO1 Rabbit pAb |
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A1518-50ul | Abclonal | 50 ul | EUR 267.6 |
NQO1 Polyclonal Antibody |
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41254-100ul | SAB | 100ul | EUR 302.4 |
NQO1 Polyclonal Antibody |
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41254-50ul | SAB | 50ul | EUR 224.4 |
NQO1 Blocking Peptide |
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33R-1274 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GOT2 antibody, catalog no. 70R-1560 |
NQO1 Blocking Peptide |
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3639BP-50 | Biovision | EUR 183.6 |
NQO1 Blocking Peptide |
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33R-9961 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of NQO1 antibody, catalog no. 70R-10256 |
NQO1 Polyclonal Antibody |
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ABP51984-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of NQO1 from Human. This NQO1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NQO1 |
NQO1 Polyclonal Antibody |
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ABP51984-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of NQO1 from Human. This NQO1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NQO1 |
NQO1 Polyclonal Antibody |
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ABP51984-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of NQO1 from Human. This NQO1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human NQO1 |
NQO1 Blocking Peptide |
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20-abx062536 | Abbexa |
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NQO1 Rabbit mAb |
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A19586 | Abclonal | 20 μL | EUR 18 |
NQO1 Rabbit mAb |
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A19586-100ul | Abclonal | 100 ul | EUR 492 |
NQO1 Rabbit mAb |
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A19586-200ul | Abclonal | 200 ul | EUR 685.2 |
NQO1 Rabbit mAb |
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A19586-20ul | Abclonal | 20 ul | EUR 265.2 |
NQO1 Rabbit mAb |
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A19586-50ul | Abclonal | 50 ul | EUR 344.4 |
NQO1 Rabbit pAb |
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A0047-100ul | Abclonal | 100 ul | EUR 369.6 |
NQO1 Rabbit pAb |
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A0047-200ul | Abclonal | 200 ul | EUR 550.8 |
NQO1 Rabbit pAb |
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A0047-20ul | Abclonal | 20 ul | EUR 219.6 |
NQO1 Rabbit pAb |
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A0047-50ul | Abclonal | 50 ul | EUR 267.6 |
Polyclonal NQO1 Antibody |
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APR08804G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NQO1 . This antibody is tested and proven to work in the following applications: |
NQO1 activator 1 |
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HY-128895 | MedChemExpress | 100mg | EUR 3159.6 |
Human NQO1 Antibody (Biotin Conjugate) |
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32959-05121 | AssayPro | 150 ug | EUR 442.8 |
Human Intracellular NQO1 ELISA Kit |
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LF-EK70031 | Abfrontier | 1×96T | EUR 722.4 |
NQO1 ELISA Kit (Human) (OKCD09345) |
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OKCD09345 | Aviva Systems Biology | 96 Wells | EUR 1090.8 |
Description: Description of target: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.122ng/mL |
NQO1 ORF Vector (Human) (pORF) |
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ORF026247 | ABM | 1.0 ug DNA | EUR 114 |
NQO1 (human intracellular) ELISA Kit |
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K4926-100 | Biovision | EUR 1149.6 |
Human NADH Dehydrogenase, Quinone 1 (NQO1) Protein |
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20-abx167110 | Abbexa |
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NQO1 Protein Vector (Human) (pPB-C-His) |
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PV104986 | ABM | 500 ng | EUR 394.8 |
NQO1 Protein Vector (Human) (pPB-N-His) |
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PV104987 | ABM | 500 ng | EUR 394.8 |
NQO1 Protein Vector (Human) (pPM-C-HA) |
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PV104988 | ABM | 500 ng | EUR 394.8 |
NQO1 Protein Vector (Human) (pPM-C-His) |
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PV104989 | ABM | 500 ng | EUR 394.8 |
Recombinant Human NQO1 Protein, His, E.coli-10ug |
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QP12875-10ug | EnQuireBio | 10ug | EUR 241.2 |
Recombinant Human NQO1 Protein, His, E.coli-1mg |
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QP12875-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human NQO1 Protein, His, E.coli-2ug |
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QP12875-2ug | EnQuireBio | 2ug | EUR 186 |
Anti-NQO1/Dt Diaphorase Rabbit Monoclonal Antibody |
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M00494 | BosterBio | 100ug/vial | EUR 476.4 |
Description: Rabbit Monoclonal NQO1/Dt Diaphorase Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
Human NQO1 AssayLite Antibody (FITC Conjugate) |
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32959-05141 | AssayPro | 150 ug | EUR 513.6 |
Human NQO1 AssayLite Antibody (RPE Conjugate) |
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32959-05151 | AssayPro | 150 ug | EUR 513.6 |
Human NQO1 AssayLite Antibody (APC Conjugate) |
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32959-05161 | AssayPro | 150 ug | EUR 513.6 |
Human NQO1 AssayLite Antibody (PerCP Conjugate) |
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32959-05171 | AssayPro | 150 ug | EUR 565.2 |
NQO1 sgRNA CRISPR Lentivector set (Human) |
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K1451001 | ABM | 3 x 1.0 ug | EUR 406.8 |
Rabbit Anti-NQO1 monoclonal antibody, clone KG551-2 |
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CABT-L877 | Creative Diagnostics | 100 ul | EUR 932.4 |
Rat NQO1 shRNA Plasmid |
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20-abx984435 | Abbexa |
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Mouse NQO1 shRNA Plasmid |
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20-abx971765 | Abbexa |
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NQO1 Antibody, HRP conjugated |
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1-CSB-PA016039LB01HU | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
NQO1 Antibody, FITC conjugated |
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1-CSB-PA016039LC01HU | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
NQO1 Antibody, Biotin conjugated |
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1-CSB-PA016039LD01HU | Cusabio |
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Description: A polyclonal antibody against NQO1. Recognizes NQO1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
NQO1 recombinant monoclonal antibody |
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A5464 | Bimake | 100ul X 3 | EUR 714 |
Description: A recombinant monoclonal antibody from rabbit against human NQO1 for WB,ELISA |
NQO1 (Isoform a) Antibody |
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abx433058-200ul | Abbexa | 200 ul | EUR 460.8 |
Polyclonal NQO1 Antibody (Internal) |
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APR08806G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human NQO1 (Internal). This antibody is tested and proven to work in the following applications: |
Mouse NADH Dehydrogenase, Quinone 1 (NQO1) Protein |
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20-abx168462 | Abbexa |
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Rat NADH Dehydrogenase, Quinone 1 (NQO1) Protein |
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20-abx650803 | Abbexa |
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NQO1 Protein Vector (Mouse) (pPB-C-His) |
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PV206430 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Mouse) (pPB-N-His) |
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PV206431 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Mouse) (pPM-C-HA) |
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PV206432 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Mouse) (pPM-C-His) |
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PV206433 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Rat) (pPB-C-His) |
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PV285894 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Rat) (pPB-N-His) |
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PV285895 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Rat) (pPM-C-HA) |
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PV285896 | ABM | 500 ng | EUR 723.6 |
NQO1 Protein Vector (Rat) (pPM-C-His) |
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PV285897 | ABM | 500 ng | EUR 723.6 |
NQO1 ELISA Kit (Human) : 96 Wells (OKEH01528) |
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OKEH01528 | Aviva Systems Biology | 96 Wells | EUR 794.4 |
Description: Description of target: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.15 ng/mL |
NQO1 sgRNA CRISPR Lentivector (Human) (Target 1) |
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K1451002 | ABM | 1.0 ug DNA | EUR 184.8 |
NQO1 sgRNA CRISPR Lentivector (Human) (Target 2) |
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K1451003 | ABM | 1.0 ug DNA | EUR 184.8 |
NQO1 sgRNA CRISPR Lentivector (Human) (Target 3) |
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K1451004 | ABM | 1.0 ug DNA | EUR 184.8 |
Monoclonal NQO1 Antibody, Clone: 4D12 |
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APR08802G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human NQO1. The antibodies are raised in Mouse and are from clone 4D12. This antibody is applicable in WB and IHC, FC, E |
Monoclonal NQO1 Antibody, Clone: EPR3309 |
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APR08803G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human NQO1. The antibodies are raised in Rabbit and are from clone EPR3309. This antibody is applicable in WB |
Monoclonal NQO1 Antibody, Clone: 1A11 |
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AMM06791G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human NQO1. The antibodies are raised in Mouse and are from clone 1A11. This antibody is applicable in WB, FC, E |
NQO1 ELISA Kit (Mouse) (OKAN05939) |
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OKAN05939 | Aviva Systems Biology | 96 Wells | EUR 950.4 |
Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.124 ng/mL |
NQO1 ELISA Kit (Rat) (OKCD02727) |
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OKCD02727 | Aviva Systems Biology | 96 Wells | EUR 1185.6 |
Description: Description of target: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.115 ng/mL |
NQO1 ELISA Kit (Mouse) (OKCD02770) |
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OKCD02770 | Aviva Systems Biology | 96 Wells | EUR 1123.2 |
Description: Description of target: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.124 ng/mL |
Nqo1 ORF Vector (Rat) (pORF) |
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ORF071474 | ABM | 1.0 ug DNA | EUR 607.2 |
NQO1 ELISA Kit (Mouse) (OKEH07089) |
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OKEH07089 | Aviva Systems Biology | 96 Wells | EUR 794.4 |
Description: Description of target: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL |
NQO1 ELISA Kit (Rat) (OKEH07090) |
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OKEH07090 | Aviva Systems Biology | 96 Wells | EUR 794.4 |
Description: Description of target: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.176 ng/mL |
Nqo1 ORF Vector (Mouse) (pORF) |
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ORF051608 | ABM | 1.0 ug DNA | EUR 607.2 |
pECMV-Nqo1-m-FLAG Plasmid |
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PVT15332 | Lifescience Market | 2 ug | EUR 390 |
NQO1 NAD(P)H Dehydrogenase Quinone 1 Human Recombinant Protein |
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PROTP15559 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: NQO1 Human Recombinant fused with a 20 amino acids His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 294 amino acids (1-274 a.a.) and having a molecular mass of 33kDa.;The NQO1 is purified by proprietary chromatographic techniques. |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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20-abx152553 | Abbexa |
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Human NADH Dehydrogenase, Quinone 1 (NQO1) CLIA Kit |
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20-abx496003 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Polyclonal Antibody (Human) |
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4-PAL969Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human NADH Dehydrogenase, Quinone 1 (NQO1) |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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SEL969Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6227.58 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human NADH Dehydrogenase, Quinone 1 (NQO1) in Tissue homogenates, cell lysates and other biological fluids. |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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SEL969Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 618.04 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human NADH Dehydrogenase, Quinone 1 (NQO1) in Tissue homogenates, cell lysates and other biological fluids. |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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SEL969Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 831.48 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human NADH Dehydrogenase, Quinone 1 (NQO1) in Tissue homogenates, cell lysates and other biological fluids. |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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SEL969Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3381.66 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human NADH Dehydrogenase, Quinone 1 (NQO1) in Tissue homogenates, cell lysates and other biological fluids. |
Human NADH Dehydrogenase, Quinone 1 (NQO1) ELISA Kit |
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4-SEL969Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human NADH Dehydrogenase, Quinone 1 (NQO1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx173717 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx173718 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx129916 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx130948 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx129279 | Abbexa |
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NADH Dehydrogenase, Quinone 1 (NQO1) Antibody |
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20-abx177714 | Abbexa |
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Polyclonal NQO1 antibody - C-terminal region |
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APR08808G | Leading Biology | 0.05mg | EUR 633.6 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NQO1 - C-terminal region. This antibody is tested and proven to work in the following applications: |
Collectively, our knowledge counsel that MOSP destined for the TDE OM follows the canonical BAM pathway, whereas formation of a secure periplasmic conformer includes an export-related, folding pathway not current in E. coli.