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Multimeric Amphipathic α-Helical Sequences for Rapid and Efficient Intracellular Protein Transport at Nanomolar Concentrations.

An amphipathic leucine (L) and lysine (Ok)-rich α-helical peptide is multimerized primarily based on helix-loop-helix buildings to maximise the penetrating actions. The multimeric LK-based cell penetrating peptides (LK-CPPs) can penetrate… Read more »