Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and protein counter-screens

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19F-NMR-based fragment screening for 14 completely different biologically lively RNAs and 10 DNA and protein counter-screens

 

We report right here on the nuclear magnetic resonance (NMR) 19 F screening of 14 RNA targets with completely different secondary and tertiary construction to systematically assess druggability of RNAs. Our RNA targets embody consultant bacterial riboswitches that naturally bind with nanomolar affinity and excessive specificity to mobile metabolites of low molecular weight.
Primarily based on counter-screens in opposition to 5 DNAs and 5 proteins, we are able to present that RNA will be particularly focused. To reveal the standard of the preliminary fragment library that has been designed for simple follow-up chemistry, we additional present the best way to enhance binding affinity from an preliminary fragment hit by chemistry that hyperlinks the recognized fragment to the intercalator acridine. Thus, we obtain low micromolar binding affinity with out dropping binding specificity between two completely different terminator buildings.

Predicting persistence of atopic dermatitis in youngsters utilizing scientific attributes and serum proteins

 

Background: Atopic dermatitis (AD) is the commonest inflammatory pores and skin illness in youngsters, with 30% of all these identified creating power or relapsing illness by adolescence. Such illness persistence can’t but be predicted. The intention of the current research was to foretell the pure course of AD utilizing scientific parameters and serum proteins.
Strategies: Sera of 144 youngsters with AD (age 0-Three years) had been analyzed for IgE and 33 cytokines, chemokines, and development components. Affected person illness course till the age of seven years was assessed retrospectively. Unsupervised k-means clustering was carried out to outline illness endotypes.
Recognized components related to AD persistence on the age of seven years had been validated in youngsters with AD in an unbiased cohort (LISA Munich; n=168). Logistic regression and XGBoosting strategies adopted by cross-validation had been utilized to foretell particular person illness outcomes.
Outcomes: Three distinct endotypes had been present in infancy, characterised by a novel inflammatory signature. Elements related to illness persistence had been illness rating (SCORAD), involvement of the limbs, flexural lesion distribution on the age of three years, allergic comorbidities and illness exacerbation by the set off components stress, pollen publicity, and alter in climate.
Persistence was predicted with a sensitivity of 81.8% and a specificity of 82.4%. Elements with a excessive impression on the prediction of persistence had been SCORAD on the age of three years, set off components, and low VEGF serum ranges.
Conclusions: AD in infancy contains three immunological endotypes. Illness persistence will be predicted utilizing serum cytokines and scientific variables.
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HER2, Active, Human Recombinant
8011-50 each
EUR 1358.4

GDA Human, Guanine Deaminase Human Recombinant Protein, Active
PROTQ9Y2T3-2 Regular: 10ug
EUR 380.4
Description: GDA Human Recombinant produced in E. coli is a single polypeptide chain containing 477 amino acids (1-454) and having a molecular mass of 53kDa.;GDA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GAPDH, Active, human recombinant
P1100-10 each
EUR 170.4

GAPDH, Active, human recombinant
P1100-50 each
EUR 470.4

Recombinant purified, human NFkB-p65 protein, active
NFKB651-R-5 5 ug
EUR 781.2

Irisin, Active, human recombinant
7852-10 each
EUR 444

Irisin, Active, human recombinant
7852-50 each
EUR 1292.4

GLUL Human, Glutamine Synthetase Human Recombinant Protein, Active
PROTP15104-1 Regular: 10ug
EUR 380.4
Description: GLUL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 373 amino acids (1-373) and having a molecular mass of 42kDa.

MGLL Human, Monoglyceride Lipase Human Recombinant Protein, Active
PROTQ99685-1 Regular: 5ug
EUR 380.4
Description: MGLL Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 333 amino acids (1-313 a.a.) and having a molecular mass of 36.4kDa. The MGLL is purified by proprietary chromatographic techniques.

GCN5 highly active Recombinant Protein
90-345 2 ug
EUR 500.1
Description: GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.

PARG highly active Recombinant Protein
90-350 2 ug
EUR 500.1
Description: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.

Purified, recombinant Human TACE control protein (active)
TACE15-R-10 10 ug
EUR 854.4

TIP60 highly active Recombinant Protein
90-347 2 ug
EUR 500.1
Description: TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-10 10 ug
EUR 534

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-10 10 ug
EUR 534

Human Recombinant VEGF165 Protein (HEK), biologically active
VEGF27-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-1000 1000 ug
EUR 11022

GUK1 Human, Guanylate Kinase 1 Human Recombinant Protein, Active
PROTQ16774-1 Regular: 10ug
EUR 380.4
Description: GUK1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 217 amino acids (1-197 a.a.)and having a total molecular mass of 23.9 kDa. ;GUK1 is fused to a 20 amino acid His Tag at N-terminus and is purified by proprietary chromatographic techniques.

NMNAT1 highly active Recombinant Protein
90-354 10 ug
EUR 437.1
Description: Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

NMNAT1 highly active Recombinant Protein
90-355 50 ug
EUR 619.8
Description: Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

NMNAT3 highly active Recombinant Protein
90-356 10 ug
EUR 468.6
Description: Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

NMNAT3 highly active Recombinant Protein
90-357 50 ug
EUR 852.9
Description: Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-10 10 ug
EUR 534

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-10 10 ug
EUR 534

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-100 100 ug
EUR 2690.4

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-1000 1000 ug
EUR 11022

MMP-9, Active, human recombinant
7867-1000 each
EUR 601.2

MMP-9, Active, human recombinant
7867-500 each
EUR 398.4

MMP-9, Active, Human Recombinant
P1567-10 10 µg
EUR 417.6

MMP-9, Active, Human Recombinant
P1567-50 50 µg
EUR 612

Recombinant (E. coli, >95%) human NFkB-p50 protein, active
NFKB501-R-5 5 ug
EUR 781.2

MMP-14, Active, Human Recombinant
8009-10 each
EUR 379.2

MMP-14, Active, Human Recombinant
8009-50 each
EUR 966

PDIA4 Human, Protein Disulfide Isomerase A4 Human Recombinant Protein, Active
PROTP13667-1 Regular: 10ug
EUR 380.4
Description: PDIA4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 646 amino acids (21-645 a.a.) and having a molecular weight of 72.9kDa. The PDIA4 is fused to 21 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

PDIA3 Human, Protein Disulfide Isomerase A3 Human Recombinant Protein, Active
PROTP30101-1 Regular: 10ug
EUR 380.4
Description: PDIA3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 518 amino acids (25-505 a.a.) and having a molecular wieght of 58.5 kDa. The PDIA3 is fused to 37 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

PDIA6 Human, Protein Disulfide Isomerase A6 Human Recombinant Protein, Active
PROTQ15084-1 Regular: 10ug
EUR 380.4
Description: PDIA6 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 442 amino acids (20-440 a.a.) and having a molecular mass of 48.5kDa. The PDIA6 is purified by proprietary chromatographic techniques.

Purified Recombinant Human BMP3 protein, Biologically active
BMP35-R-10 10 ug
EUR 489.6

Purified Recombinant Human BMP4 protein, Biologically active,
BMP45-R-10 10 ug
EUR 1074

Purified Recombinant Human BMP4 protein, Biologically active
BMP45-R-5 5 ug
EUR 634.8

Purified Recombinant Human BMP6 protein, Biologically active
BMP65-R-20 20 ug
EUR 1074

BMP-4 Bone Morphogenetic protein-4 Human Recombinant Protein, Active
PROTP12644 Regular: 10ug
EUR 380.4
Description: BMP-4 Human Recombinant produced in HEK cells is a glycosylated disulfide linked homodimer, having a total molecular weight of 34kDa.;The BMP-4 is purified by proprietary chromatographic techniques.

GLUL Human, Glutamine Synthetase Human Recombinant Protein, His Active
PROTP15104-2 Regular: 10ug
EUR 380.4
Description: GLUL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (1-373 a.a.) and having a molecular mass of 44.2 kDa. The GLUL is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Active AHCY, human recombinant
7527-10 each
EUR 314.4

Active AHCY, human recombinant
7527-1000 each
EUR 6578.4

Active AHCY, human recombinant
7527-50 each
EUR 574.8

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-1ug
QP14023-1ug 1ug
EUR 186

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-5ug
QP14023-5ug 5ug
EUR 241.2

PGP Human, Phosphoglycolate Phosphatase Human Recombinant Protein, Active
PROTA6NDG6-1 Regular: 10ug
EUR 380.4
Description: PGP Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 345 amino acids (1-321a.a) and having a molecular mass of 36.5kDa.;PGP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant RSV Active SRC Protein [GST]
VAng-Lsx0456-inquire inquire Ask for price
Description: RSV Active SRC [GST], recombinant protein from Baculovirus.

Active SIRT2, human recombinant
7698-10 each
EUR 314.4

Active SIRT2, human recombinant
7698-1000 each
EUR 5272.8

Active SIRT2, human recombinant
7698-50 each
EUR 548.4

Active SIRT7, human recombinant
7846-10 each
EUR 261.6

Active SIRT7, human recombinant
7846-50 each
EUR 705.6

PRMT1, human recombinant (Active)
4865-10 each
EUR 183.6

PRMT1, human recombinant (Active)
4865-1000 each
EUR 4600.8

PRMT1, human recombinant (Active)
4865-50 each
EUR 470.4

Cathepsin K, Active, human recombinant
7600-5 each
EUR 470.4

Cathepsin K, Active, human recombinant
7600-50 each
EUR 2734.8

PGAM2 Human, Phosphoglycerate Mutase 2 Human Recombinant Protein, Active
PROTP15259-1 Regular: 10ug
EUR 380.4
Description: PGAM2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 273 amino acids (1-253) and having a molecular mass of 30.9kDa.;PGAM2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PGAM1 Human, Phosphoglycerate Mutase 1 Human Recombinant Protein, Active
PROTP18669-1 Regular: 10ug
EUR 380.4
Description: PGAM1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 30.9 kDa. The PGAM1 is fused to a 20 amino acid His Tag at N-Terminus and purified by proprietary chromatographic techniques.

Active Recombinant Human CETP
7606-100 each
EUR 966

Active Recombinant Human CETP
7606-1000 each
EUR 5214

Active Recombinant Human CETP
7606-20 each
EUR 314.4

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-100ug
QP14023-EC-100ug 100ug
EUR 2470.8

GPT Human, Glutamic-Pyruvate Transaminase, His Tag Active Human Recombinant Protein
PROTP24298-2 Regular: 10ug
EUR 380.4
Description: GPT Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 516 amino acids (1-496) and having a molecular mass of 56.8 kDa.;GPT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant MeV Active Nucleocapsid Protein
VAng-Lsx0400-inquire inquire Ask for price
Description: Measles Active Nucleocapsid, recombinant protein from E. coli.

NAD Kinase highly active Recombinant Protein
90-353 50 ug
EUR 651.3
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis.

Mouse, GAPDH Mouse Recombinant Protein, Active
PROTP16858-1 Regular: 10ug
EUR 380.4
Description: GAPDH Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 356 amino acids (1-333a.a.) and having a molecular mass of 38.2kDa.;GAPDH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

TPI1 Human, Triosephosphate Isomerase 1 Human Recombinant Protein, Active
PROTP60174-1 Regular: 10ug
EUR 380.4
Description: TPI1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 269 amino acids (1-249a.a.) and having a molecular mass of 28.8kDa.;TPI1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GNMT Human, Glycine N-Methyltransferase Human Recombinant Protein , Active
PROTQ14749-1 Regular: 10ug
EUR 380.4
Description: GNMT Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-295 a.a) and having a molecular mass of 34.9kDa.;GNMT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

a.a.), TRAIL/APO 2 Ligand (114-281 a.a.) Human Recombinant Protein, Active
PROTP50591-2 Regular: 10ug
EUR 380.4
Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids _x000D_ (114-281) and having a molecular mass of 19.6 kDa._x000D_ The sTRAIL is purified by proprietary chromatographic techniques.

P4HB Human, Prolyl 4-Hydroxylase Beta Human Recombinant Protein, Active
PROTP07237-2 Regular: 10ug
EUR 380.4
Description: P4HB Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 512 amino acids (18-508 a.a.) and having a molecular mass of 57.5kDa. The P4HB is fused to a 21 amino acid His Tag and purified by conventional chromatography.

Recombinant purified, human Akt-2/PKB-beta protein, active
AKT25-R-10 10 ug
EUR 416.4

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03937 3µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03938 10µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03939 20µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03946 2µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03947 10µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03948 100µg Ask for price

Evaluating completely different sperm separation strategies for ART, via quantitative analysis of p53 protein

Context: Within the final 10 years, assisted reproductive applied sciences (ARTs) have supplied infertile {couples} a possibility to finish their reproductive undertaking. Nevertheless, the excessive failure price could possibly be defined with the complicated human replica system. In ART, the lower of the success is as a result of situations removed from the pure ones.
Goals: The intention of this research is to guage deoxyribonucleic acid (DNA) injury of spermatozoa earlier than and after choice procedures, utilizing a brand new approach capable of quantize sperm DNA injury.
Settings and design: They had been concerned 43 males domiciled completely in two areas with completely different Environmental Impression, HEI (excessive environmental impression) and LEI (Low environmental impression), they’re aged between 24 and 31 years with varied levels of dyspermia.
Topics and strategies: The 43 males had been divided into two teams: 21 in Group A (EIL) and 22 in Group B (EIH). The samples should be aliquoted into components of 0.5 mL: Group (a) Management, no processing; Group (b) Swim-up (SUP) from semen; Group (c) basic SUP; Group (d) density gradient centrifugation (DGC). All samples had been subjected to a quantitative dosage of p53 protein, earlier than and after processing.
Statistical evaluation used: For the event of the chance and significance of the information, the Scholar’s t-test was used.
Outcomes: From our information, it emerges that Teams D and B present a superior high quality about motility, vitality, and apoptosis indexes in comparison with different typical strategies. In Group B, apoptosis is akin to Group D, however they’ve barely decrease about motility and vitality.
Group C is the one which has decrease parameters than the opposite strategies. Concerning the analysis of p53 protein, the outcomes are conflicting with the analysis of apoptosis; in truth, in Group D, the values are considerably larger than the opposite strategies.
Conclusions: Sperm separation is a vital second in ART strategies. From our information, it emerges a better fragility of DNA within the male spermatozoa who reside completely in areas with excessive environmental impression.

Blunt E2 Expression Kit
abx098873-10rxns 10 rxns
EUR 560.4

RFP expression Adenovirus
AVP001 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made RFP expression adenovirus, provided in DMEM medium.

CFP expression Adenovirus
AVP002 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made CFP expression adenovirus, provided in DMEM medium.

GFP expression Adenovirus
AVP011 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made GFP expression adenovirus, provided in DMEM medium.

YFP expression Adenovirus
AVP012 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made YFP expression adenovirus, provided in DMEM medium.

BFP expression Adenovirus
AVP017 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made BFP expression adenovirus, provided in DMEM medium.

h OCT4 expression Adenovirus, in vivo ready
AVP013-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in PBS solution for in vivo application.

h SOX2 expression Adenovirus, in vivo ready
AVP014-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in PBS solution for in vivo application.

h LIN28 expression Adenovirus, in vivo ready
AVP015-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in PBS solution for in vivo application.

Rac1 Expression Vector Set
STA-454 1 kit
EUR 1765.2
Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant.

RhoA Expression Vector Set
STA-456 1 kit
EUR 1765.2
Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant.

Cdc42 Expression Vector Set
STA-455 1 kit
EUR 1765.2
Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant.

h ADA Expression Lentivirus
LVP923 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: ADA, containing a RFP-Blasticidin dual selection marker.

h IL6 Expression Lentivirus
LVP1144 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h CD4 Expression Lentivirus
LVP1152 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CD4, containing a RFP-Blasticidin dual selection marker.

h IL4 Expression Lentivirus
LVP1161 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL4, containing a RFP-Blasticidin dual selection marker.

h IL7 Expression Lentivirus
LVP1162 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker.

h KDR Expression Lentivirus
LVP1176 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: KDR, containing a RFP-Blasticidin dual selection marker.

h FAS Expression Lentivirus
LVP1181 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: FAS, containing a RFP-Blasticidin dual selection marker.

pAAV-MCS Expression Vector
VPK-410 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

h OCT4 expression Adenovirus
AVP013 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in DMEM medium.

h SOX2 expression Adenovirus
AVP014 1x109 IFU/ml x 50ul
EUR 418.8
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in DMEM medium.

h CDR1 Expression Lentivirus
LVP917 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CDR1, containing a RFP-Blasticidin dual selection marker.

h CD47 Expression Lentivirus
LVP918 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CD47, containing a RFP-Blasticidin dual selection marker.

h ESR1 Expression Lentivirus
LVP924 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: ESR1, containing a RFP-Blasticidin dual selection marker.

r Syn1 Expression Lentivirus
LVP925 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for rat target: Syn1, containing a RFP-Blasticidin dual selection marker.

h NME4 Expression Lentivirus
LVP932 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NME4, containing a RFP-Blasticidin dual selection marker.

h EGFR Expression Lentivirus
LVP1142 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: EGFR, containing a RFP-Blasticidin dual selection marker.

h NRP1 Expression Lentivirus
LVP1145 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h MUC1 Expression Lentivirus
LVP1148 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h CD8a Expression Lentivirus
LVP1151 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CD8a, containing a RFP-Blasticidin dual selection marker.

h PIGF Expression Lentivirus
LVP1154 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: PIGF, containing a RFP-Blasticidin dual selection marker.

h BRAF Expression Lentivirus
LVP1156 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: BRAF, containing a RFP-Blasticidin dual selection marker.

h ROS1 Expression Lentivirus
LVP1158 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: ROS1, containing a RFP-Blasticidin dual selection marker.

h CD3E Expression Lentivirus
LVP1163 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker.

h KLK3 Expression Lentivirus
LVP1171 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: KLK3, containing a RFP-Blasticidin dual selection marker.

h NEK6 Expression Lentivirus
LVP1182 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NEK6, containing a RFP-Blasticidin dual selection marker.

h NEK7 Expression Lentivirus
LVP1183 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NEK7, containing a RFP-Blasticidin dual selection marker.

h LIN28 expression Adenovirus
AVP015 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in DMEM medium.

h GPNMB Expression Lentivirus
LVP921 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: GPNMB, containing a RFP-Blasticidin dual selection marker.

h DECR1 Expression Lentivirus
LVP927 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: DECR1, containing a RFP-Blasticidin dual selection marker.

h DECR2 Expression Lentivirus
LVP928 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: DECR2, containing a RFP-Blasticidin dual selection marker.

h NMRK1 Expression Lentivirus
LVP930 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NMRK1, containing a RFP-Blasticidin dual selection marker.

h PITX3 Expression Lentivirus
LVP931 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: PITX3, containing a RFP-Blasticidin dual selection marker.

h HDAC1 Expression Lentivirus
LVP1143 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h VEGFB Expression Lentivirus
LVP1146 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h PARP1 Expression Lentivirus
LVP1149 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h IL3RA Expression Lentivirus
LVP1150 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL3RA, containing a RFP-Blasticidin dual selection marker.

h PTCH1 Expression Lentivirus
LVP1155 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: PTCH1, containing a RFP-Blasticidin dual selection marker.

h SART3 Expression Lentivirus
LVP1159 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: SART3, containing a RFP-Blasticidin dual selection marker.

h TIGIT Expression Lentivirus
LVP1160 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: TIGIT, containing a RFP-Blasticidin dual selection marker.

h EDNRA Expression Lentivirus
LVP1165 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: EDNRA containing a RFP-Blasticidin dual selection marker.

h Foxp3 Expression Lentivirus
LVP1172 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: Foxp3, containing a RFP-Blasticidin dual selection marker.

m RIKEN Expression Lentivirus
LVP1174 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for mouse target: RIKEN, containing a RFP-Blasticidin dual selection marker.

h APLP2 Expression Lentivirus
LVP1177 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: APLP2, containing a RFP-Blasticidin dual selection marker.

h PCSK9 Expression Lentivirus
LVP1178 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: PCSK9, containing a RFP-Blasticidin dual selection marker.

h NTSR1 Expression Lentivirus
LVP1179 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NTSR1, containing a RFP-Blasticidin dual selection marker.

pscAAV-MCS Expression Vector
VPK-430 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

H-Ras Expression Vector Set
STA-457 1 kit
EUR 1765.2
Description: H-Ras Expression Vector Set contains 3 vectors: H-Ras wild type, T19N dominant negative mutant, and G12V constitutively active mutant.

m CTAGA1 Expression Lentivirus
LVP916 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for mouse target: CTAGA1, containing a RFP-Blasticidin dual selection marker.

h SKIV2L Expression Lentivirus
LVP919 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: SKIV2L, containing a RFP-Blasticidin dual selection marker.

h SKIV2L Expression Lentivirus
LVP919-GP 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: SKIV2L, containing a GFP-Puromycin dual selection marker.

h TP5313 Expression Lentivirus
LVP926 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: TP5313, containing a RFP-Blasticidin dual selection marker.

h ELOVL5 Expression Lentivirus
LVP929 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: ELOVL5, containing a RFP-Blasticidin dual selection marker.

h MAGEA3 Expression Lentivirus
LVP1147 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h NANOS3 Expression Lentivirus
LVP1164 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NANOS3, containing a RFP-Blasticidin dual selection marker.

h IL1RL1 Expression Lentivirus
LVP1168 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL1RL1, containing a RFP-Blasticidin dual selection marker.

h CTAG1B Expression Lentivirus
LVP1169 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CTAG1B, containing a RFP-Blasticidin dual selection marker.

h MAGEA3 Expression Lentivirus
LVP1170 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: MAGEA3, containing a RFP-Blasticidin dual selection marker.

h COX7A1 Expression Lentivirus
LVP1173 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: COX7A1, containing a RFP-Blasticidin dual selection marker.

h BCL11B Expression Lentivirus
LVP1180 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: BCL11B, containing a RFP-Blasticidin dual selection marker.

pUC57-sgRNA expression vector
PVT18003 2 ug
EUR 309.6

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