Antibody-protein binding and conformational adjustments: figuring out allosteric signalling pathways to engineer a greater effector response
Quite a few monoclonal antibodies have been developed efficiently for the remedy of assorted ailments. Nonetheless, the event of biotherapeutic antibodies is complicated, costly, and time-consuming, and to facilitate this course of, cautious structural evaluation past the antibody binding web site is required to develop a extra efficacious antibody. On this work, we targeted on protein antigens, since they induce the most important antibody adjustments, and supply fascinating circumstances to check and distinction.
The constructions of 15 anti-protein antibodies have been analysed to check the antigen-bound/unbound types. Surprisingly, three completely different lessons of binding-induced adjustments have been recognized. In school (B1), the antigen binding fragment distorted considerably, and we discovered adjustments within the loop area of the heavy chain’s fixed area; this corresponds properly with anticipated allosteric actions. In school (B2), we discovered adjustments in the identical loop area with out the general distortion.
In school (B3), these adjustments didn’t current, and solely native adjustments on the complementarity figuring out areas have been discovered. Consequently, structural evaluation of antibodies is essential for therapeutic improvement. Cautious analysis of allosteric actions should be undertaken to develop higher effector responses, particularly throughout the transformation of those antibodies from small fragments on the discovery stage to full antibodies on the subsequent improvement phases.
Olfactory marker protein elevates basal cAMP focus
Olfactory marker protein (OMP), which is expressed abundantly in mature olfactory receptor neurons, operates as a cAMP-binding protein. OMP captures phasic cAMP surges induced by sensory stimuli and punctuates the downstream signalling within the cilia. Alternatively, OMP can be ample within the soma. At equilibrium, OMP ought to exhibit affiliation/dissociation reactions with cAMP.
To look at the steady-state perform of OMP, we expressed OMP in an HEK293 heterologous expression system and measured the exercise of cAMP-dependent protein kinase (PKA) utilizing a cAMP response component/luciferase reporter assay. Within the presence of OMP, the basal exercise degree of PKA was elevated to roughly twice as a lot as that within the absence of OMP. Upon tonic stimulation by membrane-permeable cAMP, the PKA exercise elevated in a dose-dependent method and was higher within the presence of OMP in any respect doses till saturation.
These outcomes point out that OMP, a cytosolic cAMP-binding protein, operates as a cAMP reservoir by will increase the basal cAMP focus and enhances tonic cAMP actions. Along with the earlier discovering that OMP acutely sequesters cAMP-related responses, these outcomes point out that OMP can buffer acute surges in cAMP and tonic manufacturing, which stabilizes the basal cAMP pool in the long term.
OPCD00639-50UG - UPK2 Recombinant Protein |
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OPCD00639-50UG | Aviva Systems Biology | 50ug | EUR 239 |
OPCD00639-200UG - UPK2 Recombinant Protein |
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OPCD00639-200UG | Aviva Systems Biology | 200ug | EUR 469 |
Recombinant Human Uroplakin-2/UPK2 Protein (His Tag) |
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PKSH033198-10ug | Elabscience Biotech | 10ug | EUR 178 |
Description: Human |
Recombinant Human Uroplakin-2/UPK2 Protein (His Tag) |
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PKSH033198-50ug | Elabscience Biotech | 50ug | EUR 523 |
Description: Human |
Recombinant Human Uroplakin-2 (UPK2) |
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CSB-CF025656HU | Cusabio | 9863 mg | Ask for price |
Recombinant Human Uroplakin-2/UPK2 (C-6His) |
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AP75439 | SAB | 1mg | EUR 3209 |
Recombinant Human Uroplakin-2/UPK2 (C-6His) |
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CA11-10ug | Novoprotein | 10ug | EUR 242.4 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Uroplakin-2/UPK2 (C-6His) |
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CA11-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Uroplakin-2/UPK2 (C-6His) |
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CA11-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Uroplakin-2/UPK2 (C-6His) |
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CA11-50ug | Novoprotein | 50ug | EUR 595.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Uroplakin 2 (UPK2) |
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RPU57414-100ug | Biomatik Corporation | 100ug | EUR 470.4 |
Recombinant Uroplakin 2 (UPK2) |
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RPU57414-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Uroplakin 2 (UPK2) |
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RPU57414-50ug | Biomatik Corporation | 50ug | EUR 385 |
Recombinant Uroplakin 2 (UPK2) |
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RPF561Hu01 | Cloud-Clone | 10ug | EUR 120 |
Recombinant Uroplakin 2 (UPK2) |
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4-RPF561Hu01 | Cloud-Clone |
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Description: Recombinant Human Uroplakin 2 expressed in: E.coli |
Recombinant Uroplakin 2 (UPK2) |
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RPF561Ra01 | Cloud-Clone | 10ug | EUR 140 |
Recombinant Uroplakin 2 (UPK2) |
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RPU50436-100ug | Biomatik Corporation | 100ug | EUR 369.6 |
Recombinant Uroplakin 2 (UPK2) |
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RPU50436-1mg | Biomatik Corporation | 1mg | EUR 1638 |
Recombinant Uroplakin 2 (UPK2) |
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RPU50436-50ug | Biomatik Corporation | 50ug | EUR 297 |
UPK1B Recombinant Protein (Human) |
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RP033997 | ABM | 100 ug | Ask for price |
UPK3A Recombinant Protein (Human) |
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RP034000 | ABM | 100 ug | Ask for price |
UPK3B Recombinant Protein (Human) |
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RP034003 | ABM | 100 ug | Ask for price |
UPK1A Recombinant Protein (Human) |
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RP044680 | ABM | 100 ug | Ask for price |
UPK3BL Recombinant Protein (Human) |
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RP106565 | ABM | 100 ug | Ask for price |
UPK3BP1 Recombinant Protein (Human) |
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RP106568 | ABM | 100 ug | Ask for price |
Recombinant Mouse Uroplakin-2(Upk2) |
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AP77668 | SAB | 1mg | EUR 2826 |
Recombinant Mouse Uroplakin-2 (Upk2) |
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CSB-EP025656MO | Cusabio | 2465 mg | Ask for price |
Recombinant Mouse Uroplakin-2 (Upk2) |
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RPC22210-100ug | Biomatik Corporation | 100ug | EUR 705.1 |
Recombinant Mouse Uroplakin-2 (Upk2) |
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RPC22210-1mg | Biomatik Corporation | 1mg | EUR 3237 |
Recombinant Mouse Uroplakin-2 (Upk2) |
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RPC22210-20ug | Biomatik Corporation | 20ug | EUR 353.4 |
UPK3A Uroplakin 3A Human Recombinant Protein |
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PROTO75631 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: UPK3A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 214 amino acids (19-207 a.a.) and having a molecular mass of 23.1kDa.;UPK3A is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Recombinant Human UPK3A Protein, His, E.coli-1mg |
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QP13898-1mg | EnQuireBio | 1mg | EUR 6301.2 |
Recombinant Human UPK3A Protein, His, E.coli-2ug |
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QP13898-2ug | EnQuireBio | 2ug | EUR 186 |
Recombinant Human UPK3A Protein, His, E.coli-10ug |
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QP13898-10ug | EnQuireBio | 10ug | EUR 241.2 |
UPK1A Recombinant Protein (Rat) |
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RP235931 | ABM | 100 ug | Ask for price |
UPK1B Recombinant Protein (Rat) |
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RP235934 | ABM | 100 ug | Ask for price |
UPK3A Recombinant Protein (Rat) |
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RP235940 | ABM | 100 ug | Ask for price |
UPK3BL Recombinant Protein (Rat) |
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RP235943 | ABM | 100 ug | Ask for price |
UPK1A Recombinant Protein (Mouse) |
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RP183200 | ABM | 100 ug | Ask for price |
UPK1B Recombinant Protein (Mouse) |
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RP183203 | ABM | 100 ug | Ask for price |
UPK3A Recombinant Protein (Mouse) |
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RP183209 | ABM | 100 ug | Ask for price |
UPK3B Recombinant Protein (Mouse) |
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RP183212 | ABM | 100 ug | Ask for price |
OPCD00792-10UG - UPK1A Recombinant Protein |
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OPCD00792-10UG | Aviva Systems Biology | 10ug | EUR 129 |
OPCD00792-50UG - UPK1A Recombinant Protein |
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OPCD00792-50UG | Aviva Systems Biology | 50ug | EUR 309 |
OPCD00793-10UG - UPK1A Recombinant Protein |
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OPCD00793-10UG | Aviva Systems Biology | 10ug | EUR 139 |
OPCD00793-50UG - UPK1A Recombinant Protein |
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OPCD00793-50UG | Aviva Systems Biology | 50ug | EUR 339 |
OPCD07843-10UG - UPK3A Recombinant Protein |
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OPCD07843-10UG | Aviva Systems Biology | 10ug | EUR 149 |
OPCD07843-50UG - UPK3A Recombinant Protein |
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OPCD07843-50UG | Aviva Systems Biology | 50ug | EUR 359 |
OPCD07844-10UG - UPK3A Recombinant Protein |
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OPCD07844-10UG | Aviva Systems Biology | 10ug | EUR 139 |
OPCD07844-50UG - UPK3A Recombinant Protein |
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OPCD07844-50UG | Aviva Systems Biology | 50ug | EUR 329 |
OPCD00792-200UG - UPK1A Recombinant Protein |
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OPCD00792-200UG | Aviva Systems Biology | 200ug | EUR 619 |
OPCD00793-200UG - UPK1A Recombinant Protein |
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OPCD00793-200UG | Aviva Systems Biology | 200ug | EUR 669 |
OPCD07843-200UG - UPK3A Recombinant Protein |
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OPCD07843-200UG | Aviva Systems Biology | 200ug | EUR 709 |
OPCD07844-200UG - UPK3A Recombinant Protein |
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OPCD07844-200UG | Aviva Systems Biology | 200ug | EUR 659 |
UPK3A, human recombinant |
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7188-10 | Biovision | each | EUR 366 |
UPK3A, human recombinant |
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7188-50 | Biovision | each | EUR 992.4 |
Human UPK2 Protein Lysate 20ug |
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IHUUPK2PLLY20UG | Innovative research | each | EUR 213 |
Description: Human UPK2 Protein Lysate 20ug |
Human Uroplakin 2 (UPK2) Protein |
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20-abx650668 | Abbexa |
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Human Uroplakin 2 (UPK2) Protein |
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abx650668-100g | Abbexa | 100 µg | EUR 425 |
Human Uroplakin 2 (UPK2) Protein |
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abx650668-10g | Abbexa | 10 µg | EUR 187.5 |
Human Uroplakin 2 (UPK2) Protein |
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abx650668-50g | Abbexa | 50 µg | EUR 300 |
UPK2 Protein Vector (Human) (pPM-C-HA) |
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PV059579 | ABM | 500 ng | EUR 577.2 |
Human sCD42b/GP1Ba , recombinant Human Recombinant Protein |
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S01-084 | ReliaTech | 50 µg | EUR 196.35 |
Description: CD42b, also known as GP1Ba (GP1B alpha, Glycoprotein 1Ba) is a single pass transmembrane glycoprotein that functions as the key ligand binding subunit of the GP1B platelet surface receptor. The association of CD42b/GP1Ba with GP1Bb (covalently) and platelet glycoproteins IX and V (non‐covalently) forms the von Willebrand factor receptor. The binding of von Willebrand factor (VWF) to its platelet receptor initiates the primary mechanism for the adhesion of platelets to a site of vascular injury and subsequent platelet activation. Additionally, the cytoplasmic (C‐terminal) domain of CD42b/GP1Ba can bind and activate signal transduction molecules, including 14‐3‐3ζ and β‐filamin. Mutations in von Willebrand factor and to a lesser extent, CD42b/GP1Ba, that affect the binding of VWF to the GP1B receptor are the primary cause of the hereditary bleeding disorder known as Type 2 von Willebrand disease (VWD). Mutations in the CD42b/GP1Ba gene have also been linked to a related bleeding disorder, Bernard‐Soulier disease. Recombinant Human sCD42b/GP1Ba is a 54.6 kDa protein containing 496 amino acid residues that correspond to the extracellular portion of CD42b/GP1Ba, plus a C‐terminal His‐Tag. Due to glycosylation, it migrates at approximately 100‐115 kDa by SDS‐PAGE analysis under reducing and non‐reducing conditions. |
Human sCD42b/GP1Ba , recombinant Human Recombinant Protein |
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S01-084S | ReliaTech | 10 µg | EUR 92.4 |
Description: CD42b, also known as GP1Ba (GP1B alpha, Glycoprotein 1Ba) is a single pass transmembrane glycoprotein that functions as the key ligand binding subunit of the GP1B platelet surface receptor. The association of CD42b/GP1Ba with GP1Bb (covalently) and platelet glycoproteins IX and V (non‐covalently) forms the von Willebrand factor receptor. The binding of von Willebrand factor (VWF) to its platelet receptor initiates the primary mechanism for the adhesion of platelets to a site of vascular injury and subsequent platelet activation. Additionally, the cytoplasmic (C‐terminal) domain of CD42b/GP1Ba can bind and activate signal transduction molecules, including 14‐3‐3ζ and β‐filamin. Mutations in von Willebrand factor and to a lesser extent, CD42b/GP1Ba, that affect the binding of VWF to the GP1B receptor are the primary cause of the hereditary bleeding disorder known as Type 2 von Willebrand disease (VWD). Mutations in the CD42b/GP1Ba gene have also been linked to a related bleeding disorder, Bernard‐Soulier disease. Recombinant Human sCD42b/GP1Ba is a 54.6 kDa protein containing 496 amino acid residues that correspond to the extracellular portion of CD42b/GP1Ba, plus a C‐terminal His‐Tag. Due to glycosylation, it migrates at approximately 100‐115 kDa by SDS‐PAGE analysis under reducing and non‐reducing conditions. |
UPK2 Protein Vector (Human) (pPB-C-His) |
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PV059577 | ABM | 500 ng | EUR 577.2 |
UPK2 Protein Vector (Human) (pPB-N-His) |
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PV059578 | ABM | 500 ng | EUR 577.2 |
UPK2 Protein Vector (Human) (pPM-C-His) |
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PV059580 | ABM | 500 ng | EUR 577.2 |
TAGAP Recombinant Protein (Human) (Recombinant- Tag) |
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RP030880 | ABM | 100 ug | Ask for price |
TAGLN Recombinant Protein (Human) (Recombinant- Tag) |
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RP030883 | ABM | 100 ug | Ask for price |
TAGLN Recombinant Protein (Human) (Recombinant- Tag) |
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RP030886 | ABM | 100 ug | Ask for price |
TAGAP Recombinant Protein (Human) (Recombinant- Tag) |
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RP043930 | ABM | 100 ug | Ask for price |
CTAGE1 Recombinant Protein (Human) (Recombinant- Tag) |
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RP008266 | ABM | 100 ug | Ask for price |
CTAGE5 Recombinant Protein (Human) (Recombinant- Tag) |
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RP008269 | ABM | 100 ug | Ask for price |
CTAGEP Recombinant Protein (Human) (Recombinant- Tag) |
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RP008275 | ABM | 100 ug | Ask for price |
TAGLN2 Recombinant Protein (Human) (Recombinant Tag) |
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RP030889 | ABM | 100 ug | Ask for price |
TAGLN2 Recombinant Protein (Human) (Recombinant Tag) |
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RP030892 | ABM | 100 ug | Ask for price |
TAGLN3 Recombinant Protein (Human) (Recombinant Tag) |
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RP030895 | ABM | 100 ug | Ask for price |
CTAG1A Recombinant Protein (Human) (Recombinant- Tag) |
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RP038332 | ABM | 100 ug | Ask for price |
CTAG1B Recombinant Protein (Human) (Recombinant- Tag) |
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RP038335 | ABM | 100 ug | Ask for price |
CTAGE5 Recombinant Protein (Human) (Recombinant- Tag) |
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RP038338 | ABM | 100 ug | Ask for price |
CTAGE4 Recombinant Protein (Human) (Recombinant- Tag) |
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RP053403 | ABM | 100 ug | Ask for price |
Plasma vascular adhesion protein-1 ranges correlate positively with frailty severity in older adults
Geriatric frailty is related to elevated mortality and hyperlinks to elevated inflammatory exercise. Vascular adhesion protein-1 (VAP-1) is necessary in inflammatory course of. This examine investigates the connection between plasma VAP-1 degree and frailty in older adults.
The cross-sectional examine recruited group dwelling older adults from a hospital-based complete geriatric evaluation program. The demographic knowledge, Fried Frailty Index, metabolic and inflammatory parameters have been assessed.
A complete of 151 contributors (76 girls, 50.3%) have been included within the evaluation, and the age (imply ± normal deviation) was 77.1 ± 6.1 years. The imply plasma VAP-1 degree (ng/mL) was considerably completely different (P = .029) amongst completely different frailty teams (346.3 ± 86.5 within the sturdy older adults, 371.6 ± 107.9 within the pre-frail older adults, and 416.6 ± 141.
1 within the frail older adults). Multivariate ordered logistic regression evaluation additionally demonstrated that plasma VAP-1 ranges have been positively related to frailty severity (P = .039). Evaluation of the frailty parts with plasma VAP-1 ranges confirmed that the aged who had “exhaustion” (P = .016) or “weak spot” (P = .025) tended to have greater plasma VAP-1 ranges.The information help that VAP-1 may symbolize a possible plasma biomarker of frailty.
Optogenetic management of protein binding utilizing light-switchable nanobodies
A rising variety of optogenetic instruments have been developed to reversibly management binding between two engineered protein domains. In distinction, comparatively few instruments confer light-switchable binding to a generic goal protein of curiosity.
Such a functionality would provide substantial benefits, enabling photoswitchable binding to endogenous goal proteins in cells or light-based protein purification in vitro. Right here, we report the event of opto-nanobodies (OptoNBs), a flexible class of chimeric photoswitchable proteins whose binding to proteins of curiosity may be enhanced or inhibited upon blue mild illumination.
We discover that OptoNBs are appropriate for a spread of functions together with reversibly binding to endogenous intracellular targets, modulating signaling pathway exercise, and controlling binding to purified protein targets in vitro. This work represents a step in the direction of programmable photoswitchable regulation of all kinds of goal proteins.
Prion Protein (PRNP) Antibody |
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abx114678-100l | Abbexa | 100 µl | EUR 612.5 |
Prion Protein (PRNP) Antibody |
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abx139819-100g | Abbexa | 100 µg | EUR 425 |
Prion Protein (PRNP) Antibody |
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abx101113-100l | Abbexa | 100 µl | EUR 262.5 |
Prion Protein (PRNP) Antibody |
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abx101113-1ml | Abbexa | 1 ml | EUR 712.5 |
Prion Protein (PRNP) Antibody |
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abx101113-200l | Abbexa | 200 µl | EUR 325 |
Prion Protein (PRNP) Antibody |
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abx101114-100l | Abbexa | 100 µl | EUR 262.5 |
Prion Protein (PRNP) Antibody |
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abx101114-1ml | Abbexa | 1 ml | EUR 725 |
Prion Protein (PRNP) Antibody |
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abx101114-200l | Abbexa | 200 µl | EUR 337.5 |
Prion Protein (PRNP) Antibody |
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abx174157-100l | Abbexa | 100 µl | EUR 750 |
Prion Protein (PRNP) Antibody |
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abx174157-1ml | Abbexa | 1 ml | Ask for price |
Prion Protein (PRNP) Antibody |
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abx174157-200l | Abbexa | 200 µl | Ask for price |
Prion Protein (PRNP) Antibody |
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abx319681-100l | Abbexa | 100 µl | EUR 250 |
Prion Protein (PRNP) Antibody |
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abx319681-50l | Abbexa | 50 µl | EUR 162.5 |
Prion Protein (PRNP) Antibody |
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abx431521-200l | Abbexa | 200 µl | EUR 387.5 |
Prion Protein (PRNP) Antibody |
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abx333875-100g | Abbexa | 100 µg | EUR 362.5 |
Prion Protein (PRNP) Antibody |
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abx333875-20g | Abbexa | 20 µg | EUR 162.5 |
Prion Protein (PRNP) Antibody |
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abx333875-50g | Abbexa | 50 µg | EUR 250 |
Prion Protein (PRNP) Antibody |
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abx414218-200l | Abbexa | 200 µl | EUR 512.5 |
Prion Protein (PRNP) Antibody |
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abx415314-200l | Abbexa | 200 µl | EUR 362.5 |
Prion Protein (PRNP) Antibody |
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abx415315-200l | Abbexa | 200 µl | EUR 362.5 |
Prion Protein (PRNP) Antibody |
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abx415316-200l | Abbexa | 200 µl | EUR 362.5 |
Prion Protein (PRNP) Antibody (HRP) |
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abx319682-100l | Abbexa | 100 µl | EUR 250 |
Prion Protein (PRNP) Antibody (HRP) |
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abx319682-50l | Abbexa | 50 µl | EUR 162.5 |
Prion Protein (PRNP) Antibody (HRP) |
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abx336435-100g | Abbexa | 100 µg | EUR 362.5 |
Prion Protein (PRNP) Antibody (HRP) |
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abx336435-20g | Abbexa | 20 µg | EUR 162.5 |
Prion Protein (PRNP) Antibody (HRP) |
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abx336435-50g | Abbexa | 50 µg | EUR 250 |
Prion Protein (PRNP) Antibody Pair |
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20-abx370619 | Abbexa |
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Prion Protein (PRNP) Antibody Pair |
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20-abx370620 | Abbexa |
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Prion Protein (PRNP) Antibody Pair |
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20-abx370621 | Abbexa |
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Prion Protein (PRNP) Antibody (FITC) |
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abx319683-100l | Abbexa | 100 µl | EUR 250 |
Prion Protein (PRNP) Antibody (FITC) |
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abx319683-50l | Abbexa | 50 µl | EUR 162.5 |
Prion Protein (PRNP) Antibody Pair |
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abx370619-100g | Abbexa | 100 µg | EUR 2550 |
Prion Protein (PRNP) Antibody Pair |
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abx370619-50g | Abbexa | 50 µg | EUR 1575 |
Prion Protein (PRNP) Antibody Pair |
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abx370620-100g | Abbexa | 100 µg | EUR 2312.5 |
Prion Protein (PRNP) Antibody Pair |
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abx370620-50g | Abbexa | 50 µg | EUR 1437.5 |
Prion Protein (PRNP) Antibody Pair |
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abx370621-100g | Abbexa | 100 µg | EUR 2250 |
Prion Protein (PRNP) Antibody Pair |
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abx370621-50g | Abbexa | 50 µg | EUR 1400 |
Prion Protein (PRNP) Antibody (FITC) |
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abx336436-100g | Abbexa | 100 µg | EUR 362.5 |
Prion Protein (PRNP) Antibody (FITC) |
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abx336436-20g | Abbexa | 20 µg | EUR 162.5 |
Prion Protein (PRNP) Antibody (FITC) |
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abx336436-50g | Abbexa | 50 µg | EUR 250 |
Major Prion Protein (PRNP) Antibody |
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20-abx319681 | Abbexa |
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Major Prion Protein (PRNP) Antibody |
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20-abx333875 | Abbexa |
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Major Prion Protein (PRNP) Antibody |
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20-abx002019 | Abbexa |
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Major Prion Protein (PRNP) Antibody |
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abx140599-100g | Abbexa | 100 µg | EUR 425 |
Prion Protein (PRNP) Antibody (Biotin) |
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abx319684-100l | Abbexa | 100 µl | EUR 250 |
Prion Protein (PRNP) Antibody (Biotin) |
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abx319684-50l | Abbexa | 50 µl | EUR 162.5 |
Prion Protein (PRNP) Antibody (Biotin) |
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abx336437-100g | Abbexa | 100 µg | EUR 362.5 |
Prion Protein (PRNP) Antibody (Biotin) |
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abx336437-20g | Abbexa | 20 µg | EUR 162.5 |
Prion Protein (PRNP) Antibody (Biotin) |
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abx336437-50g | Abbexa | 50 µg | EUR 250 |
Major Prion Protein (PRNP) Antibody (HRP) |
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20-abx336435 | Abbexa |
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Major Prion Protein (PRNP) Antibody (HRP) |
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20-abx319682 | Abbexa |
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Major Prion Protein (PRNP) Antibody (FITC) |
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20-abx336436 | Abbexa |
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Major Prion Protein (PRNP) Antibody (FITC) |
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20-abx319683 | Abbexa |
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Major Prion Protein (PRNP) Antibody (Biotin) |
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20-abx336437 | Abbexa |
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Major Prion Protein (PRNP) Antibody (Biotin) |
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20-abx319684 | Abbexa |
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Prion Protein (PRNP) Polyclonal Antibody |
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CAU25509-100ul | Biomatik Corporation | 100ul | EUR 229.4 |
Prion Protein (PRNP) Polyclonal Antibody |
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CAU25509-200ul | Biomatik Corporation | 200ul | EUR 287.3 |
Prion Protein (PRNP) Polyclonal Antibody |
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CAU25510-100ul | Biomatik Corporation | 100ul | EUR 222.7 |
Prion Protein (PRNP) Polyclonal Antibody |
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CAU25510-200ul | Biomatik Corporation | 200ul | EUR 278.9 |
Polyclonal Antibody to Prion Protein (PRNP) |
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PAB680Hu01 | Cloud-Clone | 100ul | EUR 232 |
Polyclonal Antibody to Prion Protein (PRNP) |
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PAB680Hu02 | Cloud-Clone | 100ul | EUR 240 |
Polyclonal Antibody to Prion Protein (PRNP) |
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PAB680Mu01 | Cloud-Clone | 100ul | EUR 239 |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse) |
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4-PAB680Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP) |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat) |
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4-PAB680Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP) |
Prion Protein (PRNP) Protein |
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abx263341-10mg | Abbexa | 10 mg | EUR 325 |
Prion Protein (PRNP) Protein |
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abx263341-25mg | Abbexa | 25 mg | EUR 1600 |
Prion Protein (PRNP) Protein |
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abx263341-5mg | Abbexa | 5 mg | EUR 225 |
Prion protein PrP (PRNP) chicken polyclonal antibody |
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CH23027-200 | Origene Technologies GmbH | 200 µl | Ask for price |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), PE |
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4-PAB680Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with PE. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), PE |
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4-PAB680Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with PE. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC |
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4-PAB680Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Cy3 |
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4-PAB680Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Cy3. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), HRP |
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4-PAB680Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with HRP. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC |
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4-PAB680Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Cy3 |
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4-PAB680Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Cy3. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), HRP |
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4-PAB680Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with HRP. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), FITC |
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4-PAB680Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with FITC. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), FITC |
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4-PAB680Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with FITC. |
Prnp (untagged) - Mouse prion protein (Prnp), (10ug) |
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MC209234 | Origene Technologies GmbH | 10 µg | Ask for price |
Eukaryotic Prion Protein (PRNP) |
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EPB680Hu61 | Cloud-Clone | 10ug | EUR 200 |
Prion protein PrP (PRNP) goat polyclonal antibody, Serum |
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AP05815PU-N | Origene Technologies GmbH | 100 µl | Ask for price |
Recombinant Prion Protein (PRNP) |
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RPU43413-100ug | Biomatik Corporation | 100ug | EUR 566.5 |
Recombinant Prion Protein (PRNP) |
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RPU43413-1mg | Biomatik Corporation | 1mg | EUR 2511.6 |
Recombinant Prion Protein (PRNP) |
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RPU43413-50ug | Biomatik Corporation | 50ug | EUR 455.4 |
Recombinant Prion Protein (PRNP) |
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RPU43414-100ug | Biomatik Corporation | 100ug | EUR 537.9 |
Recombinant Prion Protein (PRNP) |
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RPU43414-1mg | Biomatik Corporation | 1mg | EUR 2380.3 |
Recombinant Prion Protein (PRNP) |
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RPU43414-50ug | Biomatik Corporation | 50ug | EUR 431.2 |
Recombinant Prion Protein (PRNP) |
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RPB680Hu01 | Cloud-Clone | 10ug | EUR 174 |
Recombinant Prion Protein (PRNP) |
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4-RPB680Hu01 | Cloud-Clone |
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Description: Recombinant Human Prion Protein expressed in: E.coli |
Recombinant Prion Protein (PRNP) |
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RPB680Mu01 | Cloud-Clone | 10ug | EUR 184 |
Recombinant Prion Protein (PRNP) |
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4-RPB680Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Prion Protein expressed in: E.coli |